Alan Shepard, the first American in space, also holds another dubious title. He was the first person to urinate in a space suit. He was prepped and ready to go for the launch of Freedom 7, loaded into the capsule at 5:15 AM on May 5, 1961. However, due to a few technical glitches, the launch did not occur until 9:34 AM. There was no collection system in the suit at that time, so they powered down the suit and let the desperate astronaut take care of business.
Interesting Fact #2